By Amanda J. Jenkins, Y.H. Caplan
Even though the specimen of selection within the US drug trying out is urine, and serum in medical medication, curiosity has lately grown within the use of alternative matrices as drug checking out media. This ebook presents researchers and forensic toxicologists with a handy basic textual content summarizing the kingdom of data this present day. Chapters concentration particularly at the software of those practices to medicines of abuse. The up to date info supplied is complemented with thorough references.
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Pediatrics. 1992;89(1):107–13. 6. Lester BM, ElSohly M, Wright LL, Smeriglio VL, Verter J, Bauer CR, Shankaran S, Bada HS, Walls HH, Huestis MA, Finnegan LP, Maza PL. The Maternal Lifestyle Study: drug use by meconium toxicology and maternal selfreport. Pediatrics. 2001;107(2):309–17. 7. Doering PL, Boothby LA, Cheok M. Review of pregnancy labeling of prescription drugs: is the current system adequate to inform of risks? Am J Obstet Gynecol. 2002;187(2):333–9. 8. Malm H, Martikainen J, Klaukka T, Neuvonen PJ.
Drugs are stable in meconium at room temperature for up to 2 weeks, which is an important advantage for routine collections at large hospitals. Immediate refrigeration after sample collection is not always possible, and if sending to a testing laboratory, shipping on dry ice increases costs. 7. Disadvantages of Meconium Analysis There are several disadvantages associated with meconium analysis: 1. As meconium is not a homogenous sample, it is sometimes difficult to collect all neonatal discharges, which may be days apart.
Astley SJ, Little RE. Maternal marijuana use during lactation and infant development at one year. Neurotoxicol Teratol. 1990;12(2):161–8. 41. Perez-Reyes M, Wall ME. Presence of delta-9-tetrahydrocannabinol in human milk. N Engl J Med. 1982;307(13):819–20. 42. Reisner SH, Eisenberg NH, Stahl B, Hauser GJ. Maternal medications and breastfeeding. Dev Pharmacol Ther. 1983;6(5):285–304. Chapter 2 Drugs-of-Abuse in Meconium Specimens Christine M. Moore Summary Meconium is the first fecal material passed by the newborn.
Drug Testing in Alternate Biological Specimens (Forensic Science and Medicine) by Amanda J. Jenkins, Y.H. Caplan